Our laboratory generated gene expression profiles for 10 highly purified human hematopoieitic stem and progenitor cells from cord blood. Gene expression profiling was performed on Illumina arrays with a protocol optimized for maximal sensitivity on low number of cells.
This data set provides a comprehensive description of the cellular and molecular architecture of the initial steps of stem cell differentiation and lineage commitment in human hematopoiesis. Here we present a portal with pre-processed data files, which should facilitate further interrogation of the dataset.
Click on the links below to download normalized and processed data pertaining to this dataset. Raw data is available on the GEO website (accession number: GSE42414)
All differentially expression lists below were generated with the limma algorithm in R/Bioconductor as described in this table: ContrastsUsedInLaurentiEtAl.docx
- Normalized log2-transformed signal for all samples analyzed in the study: